By Robert Klitzman
Within the fifty years due to the fact DNA was once chanced on, we've seen striking advances. for instance, genetic checking out has swiftly more desirable the prognosis and therapy of illnesses reminiscent of Huntington's, cystic fibrosis, breast melanoma, and Alzheimer's. yet with this new wisdom comes tough judgements for numerous humans, who combat with worry approximately no matter if to get established, and if that is so, what to do with the consequences. Am I My Genes? indicates how genuine participants have faced those matters of their day-by-day lives.
Robert L. Klitzman interviewed sixty four those that confronted Huntington's illness, breast and ovarian melanoma, or Alpha-1 antitrypsin deficiency. The e-book describes--often within the person's personal words--how every one has wrestled with the gigantic implications that genetics has for his or her lives and their households. Klitzman exhibits how those women and men fight to make experience in their problem and its factors. They confront a chain of quandaries--whether to be established; even if to reveal their genetic dangers to folks, siblings, spouses, offspring, associates, medical professionals, insurers, employers, and faculties; how one can view and comprehend themselves and their genetics; what remedies, if any, to pursue; even if to have teenagers, undertake, reveal embryos, or abort; and even if to take part in genetic groups. within the face of those uncertainties, they've got attempted to appreciate those assessments and possibilities, keep away from fatalism, nervousness, depression, and discrimination, and locate wish, that means, and a feeling of wholeness. compelled to wander via a barren region of moving sands, they chart paths that many others could ultimately keep on with.
Klitzman captures the following the voices of pioneers, the various first to come across the non-public dilemmas brought by means of glossy genetics. Am I My Genes? is a useful account in their event, person who becomes the entire extra universal within the coming years.
"An striking exploration...probing the numerous roles and implications of genetics in our lives today.... packed with miraculous insights, this riveting ebook is key interpreting for us all." -- Paula Zahn
"Klitzman lucidly discusses the ethical and mental complexities that are available the wake of genetic testing.... an incredible ebook for an individual who has the genes for pathology, that is we all, and that i suggest it highly." -- Kay Redfield Jamison, writer of An Unquiet brain
"An illuminating voyage throughout the clinical, familial and existential quandaries confronted through these people at genetic risk." -- Thomas H. Murray, President and CEO, The Hastings heart Show
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Additional info for Am I My Genes?: Confronting Fate and Family Secrets in the Age of Genetic Testing
DNA has been successfully isolated and analyzed from a variety of biological materials. Introduction of the polymerase chain reaction (PCR) has extended the range of possible DNA samples that can be successfully analyzed because many copies are made of the DNA markers to be examined (see Chapter 4). A. 1). The most common materials tested in forensic laboratories are blood and semen or bloodstains and semen stains. BIOLOGICAL EVIDENCE AT CRIME SCENES The different types of biological evidence discussed in the previous section can be used to associate or to exclude an individual from involvement with a crime.
An average human being is composed of approximately 100 trillion cells, all of which originated from a single cell. Each cell contains the same genetic programming. Within the nucleus of our cells is a chemical substance known as DNA that contains the informational code for replicating the cell and constructing the needed enzymes. Because the DNA resides in the nucleus of the cell, it is often referred to as nuclear DNA. ) Deoxyribonucleic acid, or DNA, is sometimes referred to as our genetic blueprint because it stores the information necessary for passing down genetic attributes to future generations.
Simpson, was picked up by Los Angeles police officers and became the chief suspect in the murder investigation. J. Simpson’s successful football career and popularity, the case immediately drew the public’s attention. Over 100 pieces of biological evidence were gathered from the crime scene consisting primarily of blood droplets and stains. DNA samples were sent to three laboratories for testing. Over the summer months of 1994, the Los Angeles Police Department (LAPD) DNA Laboratory, the California Department of Justice (CA DOJ) DNA Laboratory in Berkeley, and a private contract laboratory from Maryland named Cellmark Diagnostics performed the DNA testing using both RFLP and PCR techniques.
Am I My Genes?: Confronting Fate and Family Secrets in the Age of Genetic Testing by Robert Klitzman